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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2
MGI:1917745
20 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Atp6ap2tm1.1Aich/Y
Tg(Myh6-cre)2182Mds/?
involves: C57BL/6 * FVB/N
abnormal cardiovascular system physiology J:165020
abnormal heart morphology J:165020
abnormal heart weight J:165020
decreased cardiac muscle contractility J:165020
postnatal lethality, complete penetrance J:165020
Atp6ap2tm1.1Ics/Y
involves: C57BL/6 * C57BL/6N
abnormal autophagy J:232697
Atp6ap2tm1.1Ics/Y
Tg(NPHS2-cre)295Lbh/0
involves: C57BL/6 * C57BL/6N * SJL
abnormal autophagy J:232697
abnormal cell cytoskeleton morphology J:232697
abnormal podocyte morphology J:232697
abnormal renal tubule epithelium morphology J:232697
absent proximal convoluted tubule brush border J:232697
albuminuria J:232697
decreased circulating serum albumin level J:232697
dilated renal tubules J:232697
increased blood urea nitrogen level J:232697
increased circulating cholesterol level J:232697
increased circulating creatinine level J:232697
increased podocyte apoptosis J:232697
increased urine protein level J:232697
podocyte foot process effacement J:232697
postnatal lethality, complete penetrance J:232697
renal cast J:232697

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory