Ndufab1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ndufab1
NADH:ubiquinone oxidoreductase subunit AB1
MGI:1917566

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myl1^tm1(cre)Sjb/0 Ndufab1^tm1Xiwa/Ndufab1^tm1Xiwa involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	decreased body size	J:293657
	decreased circulating insulin level	J:293657
	decreased liver glycogen level	J:293657
	decreased skeletal muscle glycogen level	J:293657
	disorganized mitochondrial cristae	J:293657
	normal homeostasis/metabolism phenotype	J:293657
	hypoglycemia	J:293657
	normal muscle phenotype	J:293657
	postnatal growth retardation	J:293657
	preweaning lethality, complete penetrance	J:293657
Tg(CAG-Ndufab1)#Xiwa/0 involves: C57BL/6J	abnormal redox activity	J:293657
	normal behavior/neurological phenotype	J:293657
	normal cellular phenotype	J:293657
	decreased brown fat cell lipid droplet size	J:293657
	decreased brown fat cell size	J:293657
	decreased circulating glucose level	J:293657
	decreased fasting circulating glucose level	J:293657
	decreased susceptibility to diet-induced obesity	J:293657
	normal homeostasis/metabolism phenotype	J:293657
	hyperactivity	J:293657
	improved glucose tolerance	J:293657
	increased carbon dioxide production	J:293657
	increased energy expenditure	J:293657
	increased insulin sensitivity	J:293657
	increased oxygen consumption	J:293657

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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