Cd2bp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd2bp2
CD2 cytoplasmic tail binding protein 2
MGI:1917483

14 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd2bp2^tm1.1Tbh/Cd2bp2^tm1.1Tbh Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * CBA/J	impaired macrophage phagocytosis	J:283435
Cd2bp2^tm1.1Tbh/Cd2bp2^tm1.1Tbh Tg(NPHS2-cre)295Lbh/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * SJL	glomerulosclerosis	J:283435
	increased mesangial cell number	J:283435
	increased urine protein level	J:283435
	podocyte foot process effacement	J:283435
	premature death	J:283435
	renal cast	J:283435
	weight loss	J:283435
Cd2bp2^tm1.1Tbh/Cd2bp2^tm1.1Tbh Tg(T-cre)1Lwd/0 B6OlaHsd.Cg-Cd2bp2^tm1.1Tbh Tg(T-cre)1Lwd	abnormal vitelline vein morphology	J:283435
	embryonic growth arrest	J:283435
	embryonic lethality during organogenesis, complete penetrance	J:283435
	hemorrhage	J:283435
Cd2bp2^tm1.1Tbh/Cd2bp2^tm1.1Tbh Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * SJL	embryonic lethality during organogenesis, complete penetrance	J:283435
Cd2bp2^tm1.2Tbh/Cd2bp2^tm1.2Tbh B6OlaHsd.129(C)-Cd2bp2^tm1.2Tbh	abnormal vitelline vein morphology	J:283435
	embryonic growth arrest	J:283435
	embryonic lethality during organogenesis, complete penetrance	J:283435
	hemorrhage	J:283435
	incomplete embryo turning	J:283435
	small visceral yolk sac	J:283435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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