Rab28 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rab28
RAB28, member RAS oncogene family
MGI:1917285

18 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rab28^em1(IMPC)J/Rab28^em1(IMPC)J C57BL/6NJ-Rab28^em1(IMPC)J/Mmjax	abnormal bone structure	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating total protein level	J:211773
	decreased heart weight	J:211773
	decreased lean body mass	J:211773
	increased circulating triglyceride level	J:211773
	increased total body fat amount	J:211773
Rab28^{tm1d(EUCOMM)Hmgu}/Rab28^{tm1d(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6J * C57BL/6N	abnormal retina cone cell morphology	J:267522
	abnormal retina cone cell outer segment morphology	J:267522
	abnormal retina outer nuclear layer thickness	J:267522
	abnormal retina pigmentation	J:267522
	decreased a-wave amplitude	J:267522
	decreased b-wave amplitude	J:267522
	increased susceptibility to age-related retinal degeneration	J:267522
	long retina cone cell outer segment	J:267522
	retina cone cell degeneration	J:267522
	short photoreceptor outer segment	J:267522
Rab28^{tm1d(EUCOMM)Wtsi}/Rab28^{tm1d(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6J * C57BL/6N	abnormal retina cone cell morphology	J:267522
	abnormal retina cone cell outer segment morphology	J:267522
	abnormal retina outer nuclear layer thickness	J:267522
	abnormal retina pigmentation	J:267522
	decreased a-wave amplitude	J:267522
	decreased b-wave amplitude	J:267522
	increased susceptibility to age-related retinal degeneration	J:267522
	long retina cone cell outer segment	J:267522
	retina cone cell degeneration	J:267522
	short photoreceptor outer segment	J:267522

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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