Spink2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spink2
serine peptidase inhibitor, Kazal type 2
MGI:1917232

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spink2^{Gt(327A6)Cmhd}/Spink2^{Gt(327A6)Cmhd} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal male germ cell apoptosis	J:175913
	abnormal seminiferous tubule morphology	J:175913
	decreased litter size	J:175913
	decreased testis weight	J:175913
	kinked sperm flagellum	J:175913
	oligozoospermia	J:175913
	reduced male fertility	J:175913
	normal reproductive system phenotype	J:175913
	small seminiferous tubules	J:175913
	small testis	J:175913
	teratozoospermia	J:175913
Spink2^{tm1.1(KOMP)Vlcg}/Spink2^{tm1.1(KOMP)Vlcg} C57BL/6N-Spink2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal epididymis morphology	J:211773
	decreased erythrocyte cell number	J:211773
	increased basophil cell number	J:211773
	male infertility	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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