Tmem127 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem127
transmembrane protein 127
MGI:1916720

30 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmem127^{tm1(KOMP)Wtsi}/Tmem127^{tm1(KOMP)Wtsi} C57BL/6N-Tmem127^{tm1(KOMP)Wtsi}/Wtsi	abnormal nail morphology	J:211773
	decreased B cell number	J:211773
	decreased B-2 B cell number	J:211773
	decreased CD4-positive, alpha-beta T cell number	J:211773
	decreased effector memory CD8-positive, alpha-beta T cell number	J:211773
	decreased KLRG1-positive NK cell number	J:211773
	decreased KLRG1-positive T-helper cell number	J:211773
	decreased Ly6C high monocyte number	J:211773
	decreased memory-marker NK cell number	J:211773
	decreased monocyte cell number	J:211773
	decreased neutrophil cell number	J:211773
	decreased NK cell number	J:211773
	decreased plasmacytoid dendritic cell number	J:211773
	increased alpha-beta T cell number	J:211773
	increased bone mineral content	J:211773
	increased CD4-positive, alpha-beta T cell number	J:211773
	increased CD8-positive, alpha-beta T cell number	J:211773
	increased CD8-positive, naive alpha-beta T cell number	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating amylase level	J:211773
	increased circulating bilirubin level	J:211773
	increased circulating creatinine level	J:211773
	increased KLRG1-positive NK cell number	J:211773
	increased Ly6C low monocyte number	J:211773
	increased memory-marker NK cell number	J:211773
	increased T cell number	J:211773
	thrombocytopenia	J:211773
	tremors	J:211773
Tmem127^tm1.1Pdah/Tmem127^tm1.1Pdah involves: BALB/cJ * C57BL/6	abnormal cell morphology	J:209071
	abnormal lysosome physiology	J:209071

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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