Tmcc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmcc2
transmembrane and coiled-coil domains 2
MGI:1916125

33 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmcc2^em1(IMPC)Mbp/Tmcc2⁺ C57BL/6N-Tmcc2^em1(IMPC)Mbp/MbpMmucd	abnormal cecum morphology	J:211773
	abnormal gallbladder morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged cecum	J:211773
	enlarged gallbladder	J:211773
	enlarged spleen	J:211773
	no spontaneous movement	J:211773
Tmcc2^em1(IMPC)Mbp/Tmcc2^em1(IMPC)Mbp C57BL/6N-Tmcc2^em1(IMPC)Mbp/MbpMmucd	abnormal placenta vasculature	J:211773
	abnormal skin appearance	J:211773
	no spontaneous movement	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Tmcc2^em1Tar/Tmcc2^em1Tar involves: C57BL/6JTar * CBA/WTar	abnormal erythrocyte morphology	J:325992
	abnormal erythroid progenitor cell morphology	J:325992
	abnormal erythropoiesis	J:325992
	anemia	J:325992
	decreased body size	J:325992
	decreased body weight	J:325992
	decreased erythrocyte cell number	J:325992
	decreased hematocrit	J:325992
	decreased hemoglobin content	J:325992
	decreased mean corpuscular hemoglobin concentration	J:325992
	extramedullary hematopoiesis	J:325992
	normal homeostasis/metabolism phenotype	J:325992
	increased erythrocyte cell number	J:325992
	increased erythroid progenitor cell number	J:325992
	increased hematocrit	J:325992
	increased hemoglobin content	J:325992
	increased mean corpuscular volume	J:325992
	increased nucleated erythrocyte cell number	J:325992
	macrocytic anemia	J:325992
	pallor	J:325992
	normal skeleton phenotype	J:325992

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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