Lamtor5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
MGI:1915826

11 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lamtor5^{tm1b(EUCOMM)Hmgu}/Lamtor5⁺ C57BL/6N-Lamtor5^{tm1b(EUCOMM)Hmgu}/Bay	abnormal coat appearance	J:211773
	abnormal skin coloration	J:211773
	decreased total retina thickness	J:211773
Lamtor5^{tm1b(EUCOMM)Hmgu}/Lamtor5^{tm1b(EUCOMM)Hmgu} C57BL/6N-Lamtor5^{tm1b(EUCOMM)Hmgu}/Bay	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Lamtor5^tm1Lye/Lamtor5^tm1Lye Not Specified	decreased insulin secretion	J:258406
Lamtor5^tm1Lye/Lamtor5^tm1Lye Tg(Ins2-cre)25Mgn/0 involves: C57BL/6 * DBA	abnormal pancreatic islet morphology	J:258406
	decreased circulating insulin level	J:258406
	decreased insulin secretion	J:258406
	normal growth/size/body region phenotype	J:258406
	impaired glucose tolerance	J:258406
	increased fasting circulating glucose level	J:258406

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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