Steap3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Steap3
STEAP family member 3
MGI:1915678

37 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Steap3^fred/Steap3^fred C57BL/6-Steap3^fred	abnormal erythrocyte physiology	J:145194
	abnormal iron homeostasis	J:145194
	anisopoikilocytosis	J:145194
	decreased circulating copper level	J:145194
	decreased hemoglobin content	J:145194
	enlarged heart	J:145194
	enlarged spleen	J:145194
	normal hematopoietic system phenotype	J:145194
	hypochromic microcytic anemia	J:145194
	increased liver copper level	J:145194
	increased liver iron level	J:145194
	leptocytosis	J:145194
	polychromatophilia	J:145194
	normal reproductive system phenotype	J:145194
	reticulocytosis	J:145194
Steap3^tm1.1Atel/Steap3^tm1.1Atel involves: C57BL/6	abnormal blood osmolality	J:154356
	abnormal erythropoiesis	J:154356
	abnormal reticulocyte morphology	J:154356
	abnormal spleen morphology	J:154356
	abnormal spleen red pulp morphology	J:154356
	abnormal vesicle-mediated transport	J:154356
	anisopoikilocytosis	J:154356
	decreased mean corpuscular hemoglobin	J:154356
	decreased mean corpuscular volume	J:154356
	decreased splenocyte apoptosis	J:154356
	extramedullary hematopoiesis	J:154356
	increased circulating glucose level	J:154356
	increased erythrocyte cell number	J:154356
	increased erythroid progenitor cell number	J:154356
	increased spleen weight	J:154356
	increased spleen white pulp amount	J:154356
	microcytic anemia	J:154356
	thrombocytosis	J:154356
Steap3^tm1.1Mdf/Steap3^tm1.1Mdf involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal erythrocyte morphology	J:103440
	abnormal iron homeostasis	J:103440
	abnormal reticulocyte morphology	J:103440
	anisopoikilocytosis	J:103440
	decreased hematocrit	J:103440
	decreased hemoglobin content	J:103440
	decreased mean corpuscular hemoglobin	J:103440
	decreased mean corpuscular hemoglobin concentration	J:103440
	decreased mean corpuscular volume	J:103440
	increased erythrocyte cell number	J:103440
	increased liver iron level	J:103440
	reticulocytosis	J:103440
	thrombocytosis	J:103440
Steap3^{tm1b(EUCOMM)Hmgu}/Steap3⁺ C57BL/6N-Steap3^{tm1b(EUCOMM)Hmgu}/J	hyperactivity	J:211773
Steap3^{tm1b(EUCOMM)Hmgu}/Steap3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Steap3^{tm1b(EUCOMM)Hmgu}/J	hyperactivity	J:211773
	impaired glucose tolerance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23