About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pclaf
PCNA clamp associated factor
MGI:1915276
23 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Pclaftm1.1Lkd/Pclaftm1.1Lkd
involves: C57BL/6
abnormal common lymphocyte progenitor cell morphology J:177782
abnormal hematopoietic stem cell physiology J:177782
abnormal hematopoietic system physiology J:177782
decreased bone marrow cell number J:177782
decreased common myeloid progenitor cell number J:177782
decreased hematopoietic stem cell number J:177782
decreased leukocyte cell number J:177782
oxidative stress J:177782
spleen hypoplasia J:177782
thymus hypoplasia J:177782
Pclaftm1a(EUCOMM)Wtsi/Pclaftm1a(EUCOMM)Wtsi
C57BL/6N-Pclaftm1a(EUCOMM)Wtsi/Wtsi
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
decreased CD11b-high dendritic cell number J:211773
decreased dendritic cell number J:211773
decreased immature NK cell number J:211773
decreased plasmacytoid dendritic cell number J:211773
decreased T cell number J:211773
increased bone mineral content J:211773
increased bone mineral density J:211773
increased CD11b-low dendritic cell number J:211773
increased dendritic cell number J:211773
increased mature NK cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased pro-B cell number J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/05/2019
MGI 6.14
The Jackson Laboratory