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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
MGI:1914762
62 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Agpat2Gt(OST438470)Lex/Agpat2Gt(OST438470)Lex
involves: 129S5/SvEvBrd * C57BL/6
abnormal brown adipose tissue morphology J:186035
abnormal dentin development J:186035
abnormal incisor morphology J:186035
abnormal liver morphology J:186035
abnormal white fat cell morphology J:186035
adipose tissue inflammation J:186035
adipose tissue necrosis J:186035
ameloblast degeneration J:186035
decreased body size J:186035
decreased brown adipose tissue amount J:186035
decreased white adipose tissue amount J:186035
decreased white fat cell number J:186035
decreased white fat cell size J:186035
distended abdomen J:186035
enlarged liver J:186035
enlarged pancreatic islets J:186035
femur fracture J:186035
granulomatous inflammation J:186035
hepatic steatosis J:186035
hyperglycemia J:186035
increased circulating glucose level J:186035
increased circulating insulin level J:186035
increased pancreatic beta cell number J:186035
lipodystrophy J:186035
liver inflammation J:186035
pale liver J:186035
postnatal lethality, incomplete penetrance J:186035
premature death J:186035
reduced enamel thickness J:186035
rough coat J:186035
Agpat2tm1Garg/Agpat2tm1Garg
involves: 129S6/SvEvTac
abnormal abdominal fat pad morphology J:146649
abnormal fatty acid level J:146649
abnormal gas homeostasis J:146649
abnormal glucose homeostasis J:146649
abnormal lipid homeostasis J:146649
abnormal phospholipid level J:146649
abnormal small intestine morphology J:146649
absent subcutaneous adipose tissue J:146649
decreased body temperature J:146649
decreased body weight J:231617
decreased brown adipose tissue amount J:146649
decreased circulating free fatty acid level J:146649
decreased circulating leptin level J:146649
decreased percent body fat/body weight J:146649
decreased respiratory quotient J:146649
decreased survivor rate J:146649
decreased total body fat amount J:146649
decreased white adipose tissue amount J:146649
enlarged pancreatic islets J:146649
hepatic steatosis J:146649
normal homeostasis/metabolism phenotype J:231617
hyperglycemia J:146649
hypoactivity J:146649
improved glucose tolerance J:231617
increased carbon dioxide production J:146649
increased circulating cholesterol level J:231617
increased circulating glucose level J:231617
increased circulating insulin level J:146649, J:231617
increased circulating triglyceride level J:146649
increased fluid intake J:146649
increased food intake J:146649, J:231617
increased kidney weight J:146649
increased liver triglyceride level J:146649, J:231617
increased liver weight J:146649, J:231617
increased oxygen consumption J:146649
increased pancreatic beta cell mass J:146649
increased spleen weight J:146649
insulin resistance J:146649, J:231617
polydipsia J:231617
postnatal lethality, incomplete penetrance J:146649

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory