C1qtnf4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

C1qtnf4
C1q and tumor necrosis factor related protein 4
MGI:1914695

8 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
C1qtnf4^em1Osb/C1qtnf4^em1Osb involves: C57BL/6NJcl * DBA/2NJcl	no abnormal phenotype detected	J:234235
C1qtnf4^em1Smoc/C1qtnf4^em1Smoc C57BL/6J-C1qtnf4^em1Smoc/Smoc	abnormal macrophage differentiation	J:302282
	increased circulating interleukin-6 level	J:302282
	increased circulating interleukin-18 level	J:302282
	increased circulating tumor necrosis factor level	J:302282
	increased susceptibility to endotoxin shock	J:302282
	increased susceptibility to induced morbidity/mortality	J:302282
	increased tumor necrosis factor secretion	J:302282

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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