Daam1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Daam1
dishevelled associated activator of morphogenesis 1
MGI:1914596

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Daam1^tm1.1Tpy/Daam1^tm1.1Tpy Daam2^tm1Tpy/Daam2^tm1Tpy Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ involves: 129S1/Sv * 129S7/SvEvBrd	abnormal A band morphology	J:228507
	abnormal H zone morphology	J:228507
	abnormal heart left ventricle morphology	J:228507
	abnormal heart right ventricle morphology	J:228507
	abnormal I band morphology	J:228507
	abnormal intercalated disk morphology	J:228507
	abnormal myocardial fiber morphology	J:228507
	abnormal myocardial fiber physiology	J:228507
	abnormal myocardial trabeculae morphology	J:228507
	absent M line	J:228507
	absent Z line	J:228507
	normal cardiovascular system phenotype	J:228507
	decreased left ventricle systolic pressure	J:228507
	decreased right ventricle systolic pressure	J:228507
	diffuse Z line	J:228507
	heart hypoplasia	J:228507
Daam1^tm1.1Tpy/Daam1^tm1.1Tpy Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd	abnormal cardiac muscle tissue morphology	J:228507
Daam1^tm1.1Tpy/Daam1^tm1.1Tpy Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Wnt5a^tm1Amc/Wnt5a⁺ involves: 129S1/Sv * 129S7/SvEvBrd	abnormal myocardial trabeculae morphology	J:228507
	thick myocardium compact layer	J:228507
Daam1^tm1.1Tpy/Daam1^tm1.1Tpy Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ Wnt5a^tm1Amc/Wnt5a^tm1Amc involves: 129S1/Sv * 129S7/SvEvBrd	abnormal heart morphology	J:228507
	abnormal heart right ventricle morphology	J:228507
	abnormal interventricular septum morphology	J:228507
	abnormal myocardial trabeculae morphology	J:228507
	abnormal myocardium compact layer morphology	J:228507
	lethality throughout fetal growth and development, complete penetrance	J:228507

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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