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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Elp1
elongator complex protein 1
MGI:1914544
101 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Elp1Gt(BGB184)Byg/Elp1Gt(BGB184)Byg
B6.129P2-Gt(BGB184)Byg
abnormal brain development J:145561
abnormal embryonic erythropoiesis J:145561
abnormal embryonic tissue morphology J:145561
abnormal vascular development J:145561
abnormal vitelline vasculature morphology J:145561
absent limb buds J:145561
absent pharyngeal arches J:145561
absent visceral yolk sac blood islands J:145561
decreased embryo size J:145561
embryonic growth arrest J:145561
embryonic lethality during organogenesis, complete penetrance J:145561
incomplete embryo turning J:145561
incomplete rostral neuropore closure J:145561
small placenta J:145561
Elp1tm1.1Gilas/Elp1tm1.1Gilas
Tg(Dct-cre)1Apdn/0
involves: 129S7/SvEvBrd * C57BL/6J
abnormal dorsal root ganglion morphology J:237480
abnormal intestinal peristalsis J:237480
abnormal neurite morphology J:237480
abnormal postural reflex J:237480
abnormal sensory neuron innervation pattern J:237480
decreased body size J:237480
decreased body weight J:237480
decreased brain weight J:237480
dorsal root ganglion degeneration J:237480
impaired coordination J:237480
increased thermal nociceptive threshold J:237480
limb grasping J:237480
postnatal growth retardation J:237480
small dorsal root ganglion J:237480
Elp1tm1.1Id/Elp1tm1.1Id
involves: 129S1/Sv * C57BL/6 * CBA
abnormal brain development J:178070
abnormal cardiac outflow tract development J:178070
abnormal cardinal vein morphology J:178070
abnormal dorsal aorta morphology J:178070
abnormal forebrain development J:178070
abnormal heart development J:178070
abnormal heart looping J:178070
abnormal telencephalon development J:178070
abnormal vitelline vasculature morphology J:178070
absent atrioventricular cushions J:178070
absent heartbeat J:178070
absent lamina terminalis J:178070
absent optic vesicle J:178070
absent second pharyngeal arch J:178070
decreased embryo size J:178070
distended pericardium J:178070
embryonic growth retardation J:178070
embryonic lethality during organogenesis, complete penetrance J:178070
pallor J:178070
pericardial effusion J:178070
Elp1tm1a(KOMP)Wtsi/Elp1tm1a(KOMP)Wtsi
B6Brd;B6Dnk;B6N-Tyrc-Brd Elp1tm1a(KOMP)Wtsi/Wtsi
preweaning lethality, complete penetrance J:211773
Elp1tm1c(KOMP)Wtsi/Elp1tm1c(KOMP)Wtsi
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
abnormal dorsal root ganglion morphology J:202989
abnormal facial morphology J:202989
abnormal nervous system physiology J:202989
abnormal neuron differentiation J:202989
abnormal sensory neuron innervation pattern J:202989
abnormal submandibular gland morphology J:202989
abnormal superior cervical ganglion morphology J:202989
decreased fetal size J:202989
decreased neuron number J:202989
decreased sensory neuron number J:202989
increased neuron apoptosis J:202989
increased neuron number J:202989
mandibular retrognathia J:202989
neonatal lethality, complete penetrance J:202989
Elp1tm1Id/Elp1tm1.1Id
Tg(Hsp70-1-cre)6Arge/0
involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
abnormal autopod morphology J:188923
abnormal dorsal root ganglion morphology J:188923
abnormal fungiform papillae morphology J:188923
abnormal gait J:188923
abnormal intestine physiology J:188923
abnormal locomotor coordination J:188923
abnormal lumbar dorsal root ganglion morphology J:188923
abnormal optic nerve innervation J:188923
abnormal placenta development J:188923
abnormal posture J:188923
abnormal sensory ganglion morphology J:188923
abnormal skeleton morphology J:188923
abnormal spongiotrophoblast layer morphology J:188923
abnormal stellate ganglion morphology J:188923
abnormal suckling behavior J:188923
abnormal superior cervical ganglion morphology J:188923
abnormal sympathetic ganglion morphology J:188923
absent gastric milk in neonates J:188923
ataxia J:188923
audiogenic seizures J:188923
blepharoptosis J:188923
conjunctivitis J:188923
decreased birth body size J:188923
decreased birth weight J:188923
decreased body length J:188923
decreased body weight J:188923
decreased survivor rate J:188923
decreased total body fat amount J:188923
distended urinary bladder J:188923
environmentally induced seizures J:188923
excessive scratching J:188923
fetal growth retardation J:188923
hydronephrosis J:188923
increased grooming behavior J:188923
increased thermal nociceptive threshold J:188923
kyphoscoliosis J:188923
kyphosis J:188923
limb grasping J:188923
neurogenic bladder J:188923
optic neuropathy J:188923
postnatal lethality, incomplete penetrance J:188923
slow postnatal weight gain J:188923
small placenta J:188923
Elp1tm1Id/Elp1tm1Id
involves: 129S1/Sv * C57BL/6
abnormal brain development J:178070
abnormal cardiac outflow tract development J:178070
abnormal cardinal vein morphology J:178070
abnormal dorsal aorta morphology J:178070
abnormal forebrain development J:178070
abnormal heart development J:178070
abnormal heart looping J:178070
abnormal telencephalon development J:178070
abnormal vitelline vasculature morphology J:178070
absent atrioventricular cushions J:178070
absent heartbeat J:178070
absent lamina terminalis J:178070
absent optic vesicle J:178070
absent second pharyngeal arch J:178070
decreased embryo size J:178070
distended pericardium J:178070
embryonic growth retardation J:178070
embryonic lethality during organogenesis, complete penetrance J:178070
pallor J:178070
pericardial effusion J:178070
Elp1tm1Id/Elp1tm1Id
Tg(Hsp70-1-cre)6Arge/0
involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
abnormal autonomic nervous system physiology J:188923
abnormal dorsal root ganglion morphology J:188923
abnormal fungiform papillae morphology J:188923
abnormal innervation pattern to muscle J:188923
abnormal intestine physiology J:188923
abnormal lumbar dorsal root ganglion morphology J:188923
abnormal muscle spindle morphology J:188923
abnormal optic disk morphology J:188923
abnormal optic nerve innervation J:188923
abnormal placenta development J:188923
abnormal posture J:188923
abnormal sensory ganglion morphology J:188923
abnormal skeleton morphology J:188923
abnormal stellate ganglion morphology J:188923
abnormal suckling behavior J:188923
abnormal superior cervical ganglion morphology J:188923
abnormal sympathetic ganglion morphology J:188923
ataxia J:188923
audiogenic seizures J:188923
blepharoptosis J:188923
conjunctivitis J:188923
decreased birth body size J:188923
decreased body length J:188923
decreased body size J:188923
decreased body weight J:188923
decreased survivor rate J:188923
decreased total body fat amount J:188923
distended urinary bladder J:188923
environmentally induced seizures J:188923
excessive scratching J:188923
fetal growth retardation J:188923
hydronephrosis J:188923
increased grooming behavior J:188923
increased thermal nociceptive threshold J:188923
kyphoscoliosis J:188923
kyphosis J:188923
limb grasping J:188923
neurogenic bladder J:188923
optic nerve atrophy J:188923
optic neuropathy J:188923
perinatal lethality, incomplete penetrance J:188923
postnatal growth retardation J:188923
slow postnatal weight gain J:188923
thin retinal ganglion layer J:188923

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory