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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pfdn1
prefoldin 1
MGI:1914449
41 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pfdn1em1(IMPC)J/Pfdn1+
C57BL/6NJ-Pfdn1em1(IMPC)J/Mmjax
abnormal locomotor behavior J:211773
decreased exploration in new environment J:211773
limb grasping J:211773
Pfdn1em1(IMPC)J/Pfdn1em1(IMPC)J
C57BL/6NJ-Pfdn1em1(IMPC)J/Mmjax
abnormal embryo size J:211773
abnormal tail morphology J:211773
cleft palate J:211773
hemorrhage J:211773
preweaning lethality, complete penetrance J:211773
Pfdn1Gt(GTR1.3)1Rul/Pfdn1Gt(GTR1.3)1Rul
involves: 129
abnormal B cell activation J:137415
abnormal B cell differentiation J:137415
abnormal B cell morphology J:137415
abnormal brain commissure morphology J:137415
abnormal brain white matter morphology J:137415
abnormal cerebellum morphology J:137415
abnormal corpus callosum morphology J:137415
abnormal erythrocyte morphology J:137415
abnormal neutrophil morphology J:137415
abnormal spleen morphology J:137415
abnormal spleen red pulp morphology J:137415
abnormal spleen white pulp morphology J:137415
abnormal splenic cell ratio J:137415
abnormal T cell activation J:137415
abnormal thymus cell ratio J:137415
abnormal thymus morphology J:137415
decreased B-1 B cell number J:137415
decreased B-2 B cell number J:137415
decreased birth body size J:137415
decreased bone marrow cell number J:137415
decreased corpus callosum size J:137415
decreased erythrocyte cell number J:137415
decreased pre-B cell number J:137415
decreased thymus weight J:137415
hydrocephaly J:137415
impaired coordination J:137415
premature death J:137415
sinus inflammation J:137415
slow postnatal weight gain J:137415
small spleen J:137415
spleen hypoplasia J:137415
thymus hypoplasia J:137415
weight loss J:137415

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory