Mtdh Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mtdh
metadherin
MGI:1914404

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mtdh^Gt(XB780)Byg/Mtdh^Gt(XB780)Byg FVB.129P2-Mtdh^Gt(XB780)Byg	abnormal branching of the mammary ductal tree	J:214244
	decreased incidence of tumors by chemical induction	J:214244
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:214244
	normal reproductive system phenotype	J:214244
Mtdh^tm1.1Dsar/Mtdh^tm1.1Dsar involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	no abnormal phenotype detected	J:216688
Mtdh^tm1.2Dsar/Mtdh⁺ either: B6.129(FVB)-Mtdh^tm1.2Dsar or (129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)	decreased litter size	J:216688
Mtdh^tm1.2Dsar/Mtdh^tm1.2Dsar either: B6.129(FVB)-Mtdh^tm1.2Dsar or (129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)	decreased cardiovascular system tumor incidence	J:216688
	decreased incidence of tumors by chemical induction	J:216688
	decreased interleukin-1 beta secretion	J:216688
	decreased interleukin-6 secretion	J:216688
	decreased litter size	J:216688
	decreased liver tumor incidence	J:216688
	decreased lung tumor incidence	J:216688
	decreased macrophage proliferation	J:216688
	decreased organ/body region tumor incidence	J:216688

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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