Oma1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Oma1
OMA1 zinc metallopeptidase
MGI:1914263

29 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Oma1^tm1Otin/Oma1^tm1Otin involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr	abnormal blood homeostasis	J:184716
	abnormal brown adipose tissue thermogenesis	J:184716
	abnormal cell physiology	J:184716
	abnormal circadian temperature homeostasis	J:184716
	abnormal gas homeostasis	J:184716
	abnormal glucose homeostasis	J:184716
	abnormal mesenteric fat pad morphology	J:184716
	abnormal mitochondrial morphology	J:184716
	decreased basal metabolism	J:184716
	decreased body temperature	J:184716
	decreased carbon dioxide production	J:184716
	decreased cellular sensitivity to alkylating agents	J:184716
	decreased circulating insulin level	J:184716
	decreased fatty acid beta-oxidation	J:184716
	decreased mitochondrial DNA content	J:184716
	decreased oxygen consumption	J:184716
	granulomatous inflammation	J:184716
	hepatic steatosis	J:184716
	impaired glucose tolerance	J:184716
	increased body weight	J:184716
	increased circulating alanine transaminase level	J:184716
	increased circulating aspartate transaminase level	J:184716
	increased circulating leptin level	J:184716
	increased circulating triglyceride level	J:184716
	increased gonadal fat pad weight	J:184716
	increased insulin sensitivity	J:184716
	increased mitochondrial size	J:184716
	increased susceptibility to diet-induced obesity	J:184716
	increased white fat cell size	J:184716

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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