Uqcrfs1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
MGI:1913944

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Uqcrfs1^tm1.1Hek/Uqcrfs1⁺ involves: C57BL/6	abnormal respiratory electron transport chain	J:179765
	abnormal survival	J:179765
	normal behavior/neurological phenotype	J:179765
	decreased basal metabolism	J:179765
	extended life span	J:179765
	premature death	J:179765
Uqcrfs1^tm1.1Hek/Uqcrfs1^tm1.1Hek involves: C57BL/6	preweaning lethality, complete penetrance	J:179765
Uqcrfs1^tm1Ctm/Uqcrfs1⁺ Not Specified	abnormal dorsoventral coat patterning	J:141714
Uqcrfs1^tm1Ctm/Uqcrfs1^tm1Ctm Not Specified	abnormal dorsoventral coat patterning	J:141714
Uqcrfs1^tm1Ctm/Uqcrfs1^tm1Ctm Tg(Camk2a-cre)#Szi/0 involves: 129 * C57BL/6 * C57BL/6J * CBA	abnormal enzyme/coenzyme activity	J:188773
	abnormal glial cell physiology	J:188773
	abnormal mitochondrial physiology	J:188773
	abnormal piriform cortex morphology	J:188773
	abnormal somatosensory cortex morphology	J:188773
	decreased body weight	J:188773
	decreased brain weight	J:188773
	decreased locomotor activity	J:188773
	hippocampal neuron degeneration	J:188773
	impaired coordination	J:188773
	increased mitochondrial fission	J:188773
	neurodegeneration	J:188773
	neuron degeneration	J:188773
	premature death	J:188773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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