Snrnp40 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Snrnp40
small nuclear ribonucleoprotein 40 (U5)
MGI:1913835

39 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Snrnp40^em1(IMPC)Bay/Snrnp40⁺ C57BL/6N-Snrnp40^em1(IMPC)Bay/BayMmucd	abnormal eye anterior chamber depth	J:211773
Snrnp40^em1(IMPC)Bay/Snrnp40^em1(IMPC)Bay C57BL/6N-Snrnp40^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
Snrnp40^em1Btlr/Snrnp40^em1Btlr C57BL/6J-Snrnp40^em1Btlr	preweaning lethality, complete penetrance	J:282417
Snrnp40^em1Btlr/Snrnp40^em2Btlr C57BL/6J-Snrnp40^em1Btlr/Snrnp40^em2Btlr	preweaning lethality, complete penetrance	J:282417
Snrnp40^em1Btlr/Snrnp40^swp C57BL/6J-Snrnp40^em1Btlr/Snrnp40^swp	abnormal bone marrow cell morphology/development	J:282417
	abnormal CD4-positive, alpha-beta T cell physiology	J:282417
	abnormal CD8-positive, alpha-beta T cell physiology	J:282417
	abnormal thymus development	J:282417
	belly spot	J:282417
	decreased B cell number	J:282417
	decreased body weight	J:282417
	decreased CD4-positive, alpha-beta T cell number	J:282417
	decreased CD8-positive, alpha-beta T cell number	J:282417
	decreased common lymphocyte progenitor cell number	J:282417
	decreased DN1 thymic pro-T cell number	J:282417
	decreased DN4 thymocyte number	J:282417
	decreased erythrocyte cell number	J:282417
	decreased hematocrit	J:282417
	decreased hemoglobin content	J:282417
	decreased lymphocyte cell number	J:282417
	decreased monocyte cell number	J:282417
	decreased NK cell number	J:282417
	decreased T cell number	J:282417
	decreased T cell proliferation	J:282417
	normal immune system phenotype	J:282417
	impaired natural killer cell mediated cytotoxicity	J:282417
	increased central memory CD8 positive, alpha-beta T cell number	J:282417
	increased circulating interferon-beta level	J:282417
	increased circulating interferon-gamma level	J:282417
	increased circulating interleukin-6 level	J:282417
	increased circulating interleukin-12 level	J:282417
	increased circulating interleukin-17 level	J:282417
	increased circulating tumor necrosis factor level	J:282417
	increased effector memory CD8-positive, alpha-beta T cell number	J:282417
	increased red blood cell distribution width	J:282417
	increased susceptibility to viral infection	J:282417
	increased susceptibility to viral infection induced morbidity/mortality	J:282417
	small thymus	J:282417
	thrombocytosis	J:282417
	thymus hypoplasia	J:282417
	white spotting	J:282417
Snrnp40^em2Btlr/Snrnp40^em2Btlr C57BL/6J-Snrnp40^em2Btlr	preweaning lethality, complete penetrance	J:282417
Snrnp40^swp/Snrnp40^swp C57BL/6J-Snrnp40^swp	belly spot	J:282417
	decreased body weight	J:282417
	white spotting	J:282417

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23