Kirrel1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kirrel1
kirre like nephrin family adhesion molecule 1
MGI:1891396

23 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kirrel1^em1(IMPC)Mbp/Kirrel1⁺ C57BL/6NCrl-Kirrel1^em1(IMPC)Mbp/MbpMmucd	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	embryonic growth retardation	J:211773
	eye hemorrhage	J:211773
	microphthalmia	J:211773
	persistence of hyaloid vascular system	J:211773
Kirrel1^em1(IMPC)Mbp/Kirrel1^em1(IMPC)Mbp C57BL/6NCrl-Kirrel1^em1(IMPC)Mbp/MbpMmucd	abnormal placenta morphology	J:211773
	embryonic growth retardation	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
Kirrel1^{Gt(VICTR20)20Lex}/Kirrel1^{Gt(VICTR20)20Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal renal glomerulus morphology	J:74230
	decreased body size	J:74230
	dilated proximal convoluted tubule	J:74230
	expanded mesangial matrix	J:74230
	increased mesangial cell number	J:74230
	increased urine protein level	J:74230
	mesangiolysis	J:74230
	postnatal lethality, incomplete penetrance	J:74230
	premature death	J:74230
	renal glomerulus cyst	J:74230
Kirrel1^tm1.2Geno/Kirrel1^tm1.2Geno involves: 129S2/SvPas * C57BL/6 * CBA	abnormal podocyte foot process morphology	J:241326
	abnormal podocyte slit diaphragm morphology	J:241326
	abnormal renal reabsorption	J:241326
	increased urine protein level	J:241326
	perinatal lethality, complete penetrance	J:241326

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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