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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lpin1
lipin 1
MGI:1891340
83 phenotypes from 4 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Lpin120884/Lpin120884
involves: C57BL/6J
abnormal action potential J:153042
abnormal gait J:153042
abnormal myelin sheath morphology J:153042
abnormal sciatic nerve morphology J:153042
decreased joint mobility J:153042
decreased nerve conduction velocity J:153042
demyelination J:153042
increased grip strength J:153042
Lpin120884/Lpin1fld
involves: BALB/cByJ * C57BL/6J
abnormal gait J:153042
abnormal myelin sheath morphology J:153042
abnormal sciatic nerve morphology J:153042
limb grasping J:153042
Lpin1fld-2J/Lpin1fld-2J
C3H/HeJ-Lpin1fld-2J/J
abnormal fat cell morphology J:66739
abnormal gait J:66739
decreased body fat mass J:66739
decreased brown adipose tissue mass J:66739
decreased brown fat cell lipid droplet size J:66739
decreased circulating leptin level J:66739
decreased white adipose tissue mass J:66739
decreased white fat cell lipid droplet size J:66739
enlarged liver J:66739
hepatic steatosis J:66739
insulin resistance J:66739
male infertility J:66739
peripheral nervous system degeneration J:66739
tremors J:66739
Lpin1fld/Lpin1fld
BALB/cByJ-Lpin1fld
abnormal aorta morphology J:63448
abnormal axon morphology J:82882
abnormal brown adipose tissue morphology J:63448
abnormal brown adipose tissue physiology J:63448
abnormal cholesterol homeostasis J:82882
abnormal enzyme/coenzyme activity J:82882
abnormal epididymal fat pad morphology J:63448
abnormal fat cell morphology J:63448, J:66739
abnormal gait J:82882
abnormal hair growth J:82882
abnormal lipid homeostasis J:82882
abnormal lipid level J:82882
abnormal motor coordination/balance J:9801
abnormal myelin sheath morphology J:82882
abnormal phospholipid level J:82882
abnormal PNS glial cell morphology J:82882
abnormal Schwann cell morphology J:82882
abnormal sciatic nerve morphology J:82882
abnormal triglyceride level J:82882
abnormal white adipose tissue physiology J:63448
axon degeneration J:82882
decreased body weight J:63448
decreased brown adipose tissue mass J:63448, J:66739
decreased brown fat cell lipid droplet size J:66739
decreased circulating LDL cholesterol level J:63448
decreased circulating leptin level J:66739
decreased circulating VLDL cholesterol level J:63448
decreased epididymal fat pad weight J:63448
decreased fatty acid level J:63448
decreased hormone-sensitive lipase activity J:63448
decreased inguinal fat pad weight J:63448
decreased insulin secretion J:63448
decreased interscapular fat pad weight J:63448
decreased lean body mass J:63448
decreased lipoprotein lipase activity J:82882
decreased survivor rate J:9801
decreased triglyceride level J:82882
decreased triglyceride lipase activity J:82882
decreased white adipose tissue mass J:63448, J:66739
decreased white fat cell lipid droplet size J:66739
delayed female fertility J:82882
disheveled coat J:82882
distended abdomen J:82882
enlarged liver J:63448, J:82882
female infertility J:82882
impaired glucose tolerance J:63448
impaired limb coordination J:9801
increased cholesterol level J:82882
increased circulating HDL cholesterol level J:63448
increased circulating insulin level J:63448
increased circulating triglyceride level J:82882
increased circulating VLDL triglyceride level J:147417
increased fatty acid level J:82882
increased liver triglyceride level J:82882, J:147417
increased triglyceride level J:82882
insulin resistance J:63448
lethality at weaning, incomplete penetrance J:9801
limb grasping J:82882
male infertility J:82882
pale liver J:82882
postnatal lethality, incomplete penetrance J:82882
premature death J:82882
retarded hair growth J:9801
ruffled hair J:82882
tremors J:82882
Lpin1fld/Lpin1fld
BALB/cByJ-Lpin1fld/J
abnormal action potential J:137213
abnormal enzyme/coenzyme level J:121022
abnormal gluconeogenesis J:121022
abnormal glucose homeostasis J:121022
abnormal metabolism J:121022
abnormal myelination J:137213
abnormal respiratory quotient J:121022
abnormal sciatic nerve morphology J:137213
decreased nerve conduction velocity J:137213
increased circulating glucose level J:121022
increased fatty acid level J:121022
increased glycogen level J:121022
limb grasping J:137213
Lpin1fld/Lpin1fld
involves: BALB/cByJ
abnormal spermatocyte morphology J:169933
Lpin1tm1Rchr/Lpin1tm1Rchr
Tg(Mpz-cre)26Mes/0
involves: 129S6/SvEvTac * FVB/N
abnormal action potential J:137213
abnormal gait J:137213
abnormal nervous system electrophysiology J:137213
abnormal Schwann cell morphology J:137213
abnormal sciatic nerve morphology J:137213
decreased nerve conduction velocity J:137213
demyelination J:137213
limb grasping J:137213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory