Srsf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Srsf4
serine and arginine-rich splicing factor 4
MGI:1890577

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Srsf4^{tm1a(EUCOMM)Wtsi}/Srsf4⁺ C57BL/6N-Srsf4^{tm1a(EUCOMM)Wtsi}/Ics	increased circulating creatinine level	J:165965
Srsf4^{tm1a(EUCOMM)Wtsi}/Srsf4^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Srsf4^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal coat/hair pigmentation	J:175295
	preweaning lethality, incomplete penetrance	J:211773
Srsf4^{tm1c(EUCOMM)Wtsi}/Srsf4^{tm1c(EUCOMM)Wtsi} Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ involves: 129S1/Sv * C57BL/6 * C57BL/6N	abnormal cardiovascular system physiology	J:344969
	abnormal fetal cardiomyocyte physiology	J:344969
	abnormal heart echocardiography feature	J:344969
	abnormal heart electrocardiography waveform feature	J:344969
	abnormal mitral valve flow	J:344969
	normal cardiovascular system phenotype	J:344969
	enlarged heart	J:344969
	heart left ventricle hypertrophy	J:344969
	increased fetal cardiomyocyte size	J:344969
	increased heart left ventricle wall thickness	J:344969
	increased heart left ventricle weight	J:344969
	increased heart rate	J:344969
	increased heart weight	J:344969
	increased myocardial fiber size	J:344969
	increased QRS amplitude	J:344969
	increased response of heart to induced stress	J:344969
	prolonged QT interval	J:344969
	shortened ST segment	J:344969

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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