Mcoln1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mcoln1
mucolipin 1
MGI:1890498

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mcoln1^tm1Asoy/Mcoln1^tm1Asoy involves: 129 * C57BL/6	abnormal gastric parietal cell morphology	J:173516
	abnormal stomach morphology	J:173516
	enlarged stomach	J:173516
	hindlimb paralysis	J:173516
	increased circulating gastrin level	J:173516
	increased stomach pH	J:173516
	postnatal growth retardation	J:173516
Mcoln1^tm1Sasl/Mcoln1^tm1Sasl involves: 129S6/SvEvTac * C57BL/6	abnormal gait	J:135368
	abnormal macrophage physiology	J:189070
	abnormal nervous system morphology	J:135368
	abnormal optic nerve morphology	J:135368
	abnormal retina outer nuclear layer morphology	J:135368
	abnormal stomach mucosa morphology	J:135368
	absent subcutaneous adipose tissue	J:135368
	decreased body weight	J:135368
	decreased brain size	J:135368
	decreased skeletal muscle mass	J:135368
	dilated cardiomyopathy	J:135368
	distended abdomen	J:135368
	distended urinary bladder	J:135368
	hindlimb paralysis	J:135368
	hunched posture	J:135368
	increased circulating gastrin level	J:135368
	lethargy	J:135368
	limb grasping	J:135368
	premature death	J:135368
	retina degeneration	J:135368
	short stride length	J:135368
	thin retina inner nuclear layer	J:135368
	thin retina inner plexiform layer	J:135368
	weakness	J:135368

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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