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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gsk3b
glycogen synthase kinase 3 beta
MGI:1861437
33 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Apctm1Tno/Apctm1Tno
Gsk3atm1Jrw/Gsk3atm1Jrw
Gsk3btm2Jrw/Gsk3btm2Jrw
involves: 129 * C57BL/6 * CBA
abnormal urinary bladder urothelium morphology J:164579
Gsk3atm1a(EUCOMM)Wtsi/Gsk3a+
Gsk3btm1Grc/Gsk3b+
involves: 129S6/SvEvTac * C57BL/6N
cleft palate J:195008
Gsk3atm1a(EUCOMM)Wtsi/Gsk3a+
Gsk3btm1Grc/Gsk3btm1Grc
involves: 129S6/SvEvTac * C57BL/6N
cleft palate J:195008
Gsk3atm1Dral/Gsk3atm1Dral
Gsk3btm1Dral/Gsk3btm1Dral
involves: 129P2/OlaHsd
abnormal behavioral response to xenobiotic J:200517
abnormal long term depression J:200517
abnormal response to new environment J:200517
decreased coping response J:200517
enhanced cued conditioning behavior J:200517
hyperactivity J:200517
impaired contextual conditioning behavior J:200517
increased anxiety-related response J:200517
increased circulating corticosterone level J:200517
increased circulating interleukin-6 level J:200517
increased thigmotaxis J:200517
Gsk3atm1Dral/Gsk3atm1Dral
Gsk3btm1Dral/Gsk3btm1Dral
involves: 129P2/OlaHsd * C57BL/6 * CBA
normal homeostasis/metabolism phenotype J:98263
increased liver glycogen level J:98263
Gsk3atm1Dral/Gsk3atm1Dral
Gsk3btm1Dral/Gsk3btm1Dral
Gys1tm1.1Arte/Gys1tm1.1Arte
involves: 129P2/OlaHsd * C57BL/6J
abnormal glycogen homeostasis J:167911
Gsk3btm1Jrw/Gsk3b+
Insrtm1Dac/Insr+
involves: 129 * C57BL/6J
abnormal circulating glucose level J:135659
abnormal circulating insulin level J:135659
decreased pancreatic beta cell mass J:135659
improved glucose tolerance J:135659
insulin resistance J:135659
Gsk3btm1Jrw/Gsk3b+
Irs2tm1Mfw/Irs2tm1Mfw
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal circulating glucose level J:135659
abnormal pancreatic islet cell apoptosis J:135659
normal growth/size/body region phenotype J:135659
increased circulating glucose level J:135659
increased circulating insulin level J:135659
increased pancreatic beta cell proliferation J:135659
insulin resistance J:135659
Gsk3btm1Jrw/Gsk3b+
Runx2tm1Kish/Runx2+
involves: 129 * 129P2/OlaHsd * C57BL/6
abnormal clavicle morphology J:129364
abnormal fontanelle morphology J:129364
Gsk3btm1Jrw/Gsk3b+
Tph2tm1Mca/Tph2tm1Mca
involves: 129 * 129S6/SvEvTac * C57BL/6J
abnormal social investigation J:131619
normal behavior/neurological phenotype J:131619
Gsk3btm2Jrw/Gsk3btm2Jrw
Irs2tm1Mfw/Irs2tm1Mfw
Tg(Ins2-cre)23Herr/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal circulating glucose level J:135659
increased circulating insulin level J:135659
Tg(GSK3B*S9A)1Vln/0
Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln
involves: FVB
abnormal axon morphology J:100971
normal behavior/neurological phenotype J:100971
impaired coordination J:100971
normal muscle phenotype J:100971
Tg(GSK3B*S9A)1Vln/0
Tg(Thy1-MAPT)2Vln/Tg(Thy1-MAPT)2Vln
involves: FVB
abnormal axon morphology J:100971
normal behavior/neurological phenotype J:100971
impaired coordination J:100971
normal muscle phenotype J:100971

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory