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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gucy1b1
guanylate cyclase 1, soluble, beta 1
MGI:1860604
29 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gucy1b1tm1.1Frb/Gucy1b1tm1.1Frb
involves: 129 * C57BL/6 * FVB/N
abnormal cecum morphology J:121321
abnormal intestinal transit time J:121321
abnormal intestine morphology J:121321
abnormal platelet activation J:121321
abnormal systemic arterial blood pressure J:121321
abnormal vasodilation J:121321
decreased body weight J:121321
dilated esophagus J:121321
dilated gallbladder J:121321
distended cecum J:121321
embryonic lethality between implantation and somite formation, complete penetrance J:121321
enlarged cecum J:121321
enlarged stomach J:121321
increased systemic arterial systolic blood pressure J:121321
intestinal hypoperistalsis J:121321
neonatal lethality, incomplete penetrance J:121321
peritoneal inflammation J:121321
postnatal growth retardation J:121321
premature death J:121321
Gucy1b1tm1.1Frb/Gucy1b1tm1.1Frb
involves: 129X1/SvJ
normal nervous system phenotype J:153212
Gucy1b1tm1.2Frb/Gucy1b1tm1.2Frb
X/Tg(Myh11-icre/ERT2)1Soff
B6.Cg-Gucy1b1tm1.2Frb Tg(Myh11-icre/ERT2)1Soff
abnormal systemic arterial blood pressure J:186053
decreased vasodilation J:186053
hypertension J:186053
increased systemic arterial systolic blood pressure J:186053
Gucy1b1tm1Zhen/Gucy1b1tm1Zhen
B6.129P2-Gucy1b1tm1Zhen
no abnormal phenotype detected J:177066
Gucy1b1tm1Zhen/Gucy1b1tm1Zhen
Tg(Pf4-icre)Q3Rsko/0
involves: 129P2/OlaHsd * C57BL/6J
abnormal platelet physiology J:177066
normal cardiovascular system phenotype J:177066
decreased platelet aggregation J:177066
decreased susceptibility to induced thrombosis J:177066
normal hematopoietic system phenotype J:177066
increased bleeding time J:177066

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory