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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mefv
Mediterranean fever
MGI:1859396
9 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mefvtm1Bhk/Mefvtm1Bhk
129S6/SvEvTac-Mefvtm1Bhk
normal immune system phenotype J:192443
increased interleukin-1 beta secretion J:192443
increased interleukin-18 secretion J:192443
Mefvtm1Chae/Mefvtm1Chae
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6)
abnormal body temperature homeostasis J:82763
decreased macrophage apoptosis J:82763
increased inflammatory response J:82763
increased susceptibility to endotoxin shock J:82763
Mefvtm2.1(MEFV)Chae/Mefv+
chimera involves: 129S6/SvEvTac
abnormal male reproductive system physiology J:172117
Mefvtm6Chae/Mefvtm6Chae
B6.129S6-Mefvtm6Chae
no abnormal phenotype detected J:172117

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory