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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
MGI:1858236
24 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Celsr3tm1Agof/Celsr3tm1Agof
either: CD-1.129P2-Celsr3tm1Agof or (involves: 129P2/OlaHsd * C57BL/6 * CD-1) 		abnormal axon guidance J:98367
abnormal brain morphology J:98367
abnormal cerebral cortex morphology J:98367
abnormal cortical marginal zone morphology J:98367
abnormal globus pallidus morphology J:98367
abnormal nervous system tract morphology J:98367
abnormal pulmonary alveolus morphology J:98367
absent anterior commissure J:98367
absent brain internal capsule J:98367
atelectasis J:98367
cyanosis J:98367
decreased corticospinal tract size J:98367
distended duodenum J:98367
impaired coordination J:98367
meteorism J:98367
neonatal lethality, complete penetrance J:98367
respiratory failure J:98367
Celsr3tm1Agof/Celsr3tm2Agof
Emx1tm1(cre)Krj/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal anterior commissure morphology J:134879
abnormal brain internal capsule morphology J:134879
abnormal corticospinal tract morphology J:134879
Celsr3tm1Agof/Celsr3tm2Agof
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd 		abnormal brain internal capsule morphology J:134879
abnormal corticospinal tract morphology J:134879
absent anterior commissure J:134879
Celsr3tm1Agof/Celsr3tm2Agof
Tg(Gsx2-icre)1Kess/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		normal nervous system phenotype J:134879
Celsr3tm1Agof/Celsr3tm2Agof
Tg(Gsx2-icre)1Kess/0
Tg(Nkx2-1-cre)1Wdr/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		normal nervous system phenotype J:134879
Celsr3tm1Agof/Celsr3tm2Agof
Tg(mI56i-cre,EGFP)1Kc/0
involves: 129P2/OlaHsd * FVB/N 		abnormal brain internal capsule morphology J:134879
abnormal corticospinal tract morphology J:134879
Celsr3tm1Agof/Celsr3tm2Agof
Tg(Nkx2-1-cre)1Wdr/0
involves: 129P2/OlaHsd 		normal nervous system phenotype J:134879
Celsr3tm1Mrc/Celsr3tm1Mrc
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S6/SvEvTac * C57BL/6NCr) 		abnormal embryonic/fetal subventricular zone morphology J:149145
abnormal globus pallidus morphology J:149145
abnormal innervation J:149145
abnormal neuronal migration J:149145
neonatal lethality, complete penetrance J:149145
normal nervous system phenotype J:149145
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory