90 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd19tm1(cre)Cgn/Cd19+ Gt(ROSA)26Sortm5(Map3k14)Rsky/Gt(ROSA)26Sortm5(Map3k14)Rsky involves: 129P2/OlaHsd * C57BL/6	enlarged lymph nodes	J:139293
	enlarged spleen	J:139293
	increased marginal zone B cell number	J:139293
	increased mature B cell number	J:139293
Cd19tm1(cre)Cgn/Cd19+ Gt(ROSA)26Sortm6(Map3k14*)Rsky/Gt(ROSA)26Sortm6(Map3k14*)Rsky involves: 129P2/OlaHsd * C57BL/6	abnormal Peyer's patch morphology	J:139293
	abnormal spleen B cell follicle morphology	J:139293
	decreased B-1 B cell number	J:139293
	enlarged lymph nodes	J:139293
	enlarged spleen	J:139293
	increased mature B cell number	J:139293
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ Map3k14tm1.1Gne/Map3k14tm1.1Gne B6(Cg)-Map3k14tm1.1Gne Gt(ROSA)26Sortm9(cre/ESR1)Arte	abnormal immunoglobulin level	J:240453
	decreased B cell number	J:240453
	decreased B cell proliferation	J:240453
	decreased germinal center B cell number	J:240453
	decreased IgA level	J:240453
	decreased IgG1 level	J:240453
	decreased IgM level	J:240453
	decreased Peyer's patch number	J:240453
	normal immune system phenotype	J:240453
Map3k14aly/Map3k14aly C57BL/6J-Map3k14aly	absent lymph nodes	J:16865
	increased susceptibility to infection	J:16865
	premature death	J:16865
Map3k14aly/Map3k14aly involves: AEJ/GnRk * C57BL/6J	abnormal immune system morphology	J:54529
	abnormal lymphocyte morphology	J:16865
	abnormal lymphopoiesis	J:16865
	abnormal mammary gland development	J:16865
	abnormal spleen primary B follicle morphology	J:54529
	absent follicular dendritic cells	J:54529
	absent lymph nodes	J:16865, J:54529
	absent Peyer's patches	J:16865, J:54529
	absent spleen marginal zone	J:54529
	absent thymus corticomedullary boundary	J:16865, J:54529
	decreased B cell number	J:54529
	decreased IgA level	J:16865, J:54529
	decreased IgG level	J:16865, J:54529
	decreased IgM level	J:16865, J:54529
	decreased spleen B cell follicle number	J:16865
	increased length of allograft survival	J:16865
	normal mortality/aging	J:16865
Map3k14aly/Map3k14aly involves: C57BL/6J	abnormal bile duct morphology	J:48224
	abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology	J:87993, J:128211
	abnormal dendritic cell antigen presentation	J:128211
	abnormal dendritic cell physiology	J:128211
	abnormal hepatobiliary system morphology	J:48224
	abnormal immune system morphology	J:147681
	abnormal immune system physiology	J:147681
	abnormal intestinal epithelium morphology	J:126867
	abnormal intestinal goblet cell morphology	J:135748
	abnormal mammary fat pad morphology	J:117313
	abnormal mammary gland development	J:117313
	abnormal NK T cell morphology	J:120659
	abnormal salivary gland morphology	J:38580, J:48224
	abnormal T cell activation	J:38580
	abnormal thymus corticomedullary boundary morphology	J:87993
	abnormal thymus medulla morphology	J:87993
	absent Peyer's patches	J:120659
	bile duct hyperplasia	J:48224
	bile duct inflammation	J:48224
	bile duct proliferation	J:48224
	decreased circulating interferon-gamma level	J:120659
	decreased circulating interleukin-4 level	J:120659
	decreased dendritic cell number	J:128211
	decreased IgE level	J:135748
	decreased mammary fat pad weight	J:117313
	decreased mast cell number	J:135748
	decreased NK T cell number	J:120659
	decreased regulatory T cell number	J:128211
	dilated bile duct	J:48224
	increased eosinophil cell number	J:135748
	increased inflammatory response	J:38580, J:48224
	increased susceptibility to parasitic infection	J:135748
	kidney inflammation	J:38580
	lacrimal gland inflammation	J:38580
	liver inflammation	J:48224
	lung inflammation	J:48224
	pancreas inflammation	J:48224
	small thymus	J:147681
	thymus cyst	J:147681
Map3k14m1Btlr/Map3k14m1Btlr C57BL/6J-Map3k14m1Btlr	abnormal B cell activation	J:152065
	absent lymph nodes	J:152065
	arrested B cell differentiation	J:152065
	decreased B cell number	J:152065
	decreased IgG level	J:152065
Map3k14m1Btlr/Map3k14m1Btlr involves: C57BL/6J	abnormal class switch recombination	J:185495
	arrested B cell differentiation	J:185495
	decreased IgG level	J:185495
Map3k14tm1.1Gne/Map3k14tm1.1Gne Cd19tm1(cre)Cgn/Cd19+ involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NTac	decreased B cell number	J:280549
Map3k14tm1.2Gne/Map3k14tm1.2Gne B6(Cg)-Map3k14tm1.2Gne	abnormal B cell physiology	J:240453
	abnormal spleen marginal zone morphology	J:240453
	abnormal thymus cell ratio	J:240453
	absent inguinal lymph nodes	J:240453
	absent Peyer's patches	J:240453
	absent popliteal lymph nodes	J:240453
	decreased B cell number	J:240453
	decreased B-2 B cell number	J:240453
	decreased follicular B cell number	J:240453
	decreased germinal center B cell number	J:240453
	decreased IgA level	J:240453
	decreased marginal zone B cell number	J:240453
	decreased transitional stage T1 B cell number	J:240453
	decreased transitional stage T2 B cell number	J:240453
	small axillary lymph nodes	J:240453
	small brachial lymph nodes	J:240453
Map3k14tm1Rds/Map3k14tm1Rds involves: 129	abnormal class switch recombination	J:188560
Map3k14tm1Rds/Map3k14tm1Rds involves: 129/Sv * C57BL/6	abnormal spleen morphology	J:68125
	abnormal thymus morphology	J:68125
	absent axillary lymph nodes	J:68125
	absent cervical lymph nodes	J:68125
	absent inguinal lymph nodes	J:68125
	absent lymph nodes	J:68125
	absent mesenteric lymph nodes	J:68125
	absent Peyer's patches	J:68125
	absent popliteal lymph nodes	J:68125
	decreased IgA level	J:68125
	decreased IgG2b level	J:68125
	decreased immunoglobulin level	J:68125