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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nucb2
nucleobindin 2
MGI:1858179
12 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nucb2Gt(OST287865)Lex/Nucb2Gt(OST287865)Lex
involves: 129S5/SvEvBrd * C57BL/6J 		decreased heart rate J:103485
increased circulating alkaline phosphatase level J:103485
Nucb2tm1.1Vdix/Nucb2tm1.1Vdix
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 		normal growth/size/body region phenotype J:270674
impaired glucose tolerance J:270674
insulin resistance J:270674
Nucb2tm1.1Vdix/Nucb2tm1.1Vdix
Tg(Adipoq-cre/Esr1*)1Evdr/0
involves: 129 * C57BL/6 		abnormal glucose homeostasis J:270674
normal growth/size/body region phenotype J:270674
Nucb2tm1.2Vdix/Nucb2tm1.2Vdix
involves: C57BL/6 		abnormal glucose homeostasis J:270674
normal adipose tissue phenotype J:270674
normal growth/size/body region phenotype J:270674
normal homeostasis/metabolism phenotype J:270674
increased circulating free fatty acids level J:270674
increased hepatic glucose production J:270674
increased interleukin-1 beta secretion J:270674
increased tumor necrosis factor secretion J:270674
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory