Tslp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tslp
thymic stromal lymphopoietin
MGI:1855696

22 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tslp^{tm1(KOMP)Vlcg}/Tslp^{tm1(KOMP)Vlcg} involves: C57BL/6 * C57BL/6NTac	abnormal airway responsiveness	J:187770
	abnormal immune system physiology	J:187770
	abnormal immunoglobulin level	J:187770
	abnormal T-helper 2 cell differentiation	J:187770
	decreased acute inflammation	J:187770
	decreased circulating interleukin-4 level	J:187770
	increased interferon-gamma secretion	J:187770
	respiratory system inflammation	J:187770
Tslp^tm1.1Pcn/Tslp^tm1.1Pcn Tg(KRT14-cre)1Ipc/0 involves: 129 * C57BL/6 * SJL	decreased eosinophil cell number	J:146511
	decreased IgE level	J:146511
	decreased lymphocyte cell number	J:146511
	decreased physiological sensitivity to xenobiotic	J:146511
Tslp^tm1.1Pcn/Tslp^tm1.1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 involves: 129 * C57BL/6 * SJL	decreased physiological sensitivity to xenobiotic	J:146511
Tslp^tm1.2Pcn/Tslp^tm1.2Pcn involves: 129 * C57BL/6 * SJL	decreased physiological sensitivity to xenobiotic	J:146511
Tslp^tm1Mak/Tslp^tm1Mak B6.Cg-Tslp^tm1Mak	colitis	J:175844
	normal digestive/alimentary phenotype	J:175844
	normal immune system phenotype	J:175844
	increased susceptibility to xenobiotic induced morbidity/mortality	J:175844
	weight loss	J:175844
Tslp^tm1Sfz/Tslp^tm1Sfz C.129(Cg)-Tslp^tm1Sfz	normal immune system phenotype	J:199558
Tslp^tm1Sfz/Tslp^tm1Sfz C.129(Cg)-Tslp^tm1Sfz	normal integument phenotype	J:199558
Tslp^tm1Sfz/Tslp^tm1Sfz involves: 129	abnormal interleukin secretion	J:197193
	abnormal T-helper 2 physiology	J:197193
	increased interleukin-5 secretion	J:197193
	increased interleukin-13 secretion	J:197193

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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