Nono Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nono
non-POU-domain-containing, octamer binding protein
MGI:1855692

23 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nono^em1(IMPC)Bay/Y C57BL/6N-Nono^em1(IMPC)Bay/BayMmucd	decreased exploration in new environment	J:211773
Nono^em1(IMPC)Bay/Nono^em1(IMPC)Bay C57BL/6N-Nono^em1(IMPC)Bay/BayMmucd	decreased exploration in new environment	J:211773
Nono^{Gt(E086B07)Wrst}/Y chimera involves: 129P2/OlaHsd	abnormal gastrulation	J:160967
Nono^{Gt(E089G04)Wrst}/Y chimera involves: 129P2/OlaHsd	no abnormal phenotype detected	J:160967
Nono^{Gt(P030B07)Wrst}/Y chimera involves: 129P2/OlaHsd	abnormal gastrulation	J:160967
Nono^{Gt(YHA266)Byg}/Y involves: 129P2/OlaHsd	abnormal craniofacial morphology	J:294120
	normal behavior/neurological phenotype	J:294120
	cardiac interstitial fibrosis	J:294120
	normal cardiovascular system phenotype	J:294120
	decreased body weight	J:294120
	decreased fibroblast cell migration	J:294120
	decreased heart weight	J:294120
	decreased kidney weight	J:294120
	decreased left ventricle diastolic pressure	J:294120
	decreased liver weight	J:294120
	decreased survivor rate	J:294120
	normal homeostasis/metabolism phenotype	J:294120
	increased fibroblast proliferation	J:294120
	preweaning lethality, incomplete penetrance	J:294120
	small heart	J:294120
Nono^{Gt(YHA266)Byg}/Y involves: 129P2/OlaHsd * C57BL/6J	abnormal cell cycle	J:193286
	abnormal liver physiology	J:193286
	delayed cellular replicative senescence	J:193286
	impaired wound healing	J:193286
	increased fibroblast proliferation	J:193286
	shortened circadian behavior period	J:189236, J:193286

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23