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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Chek2
checkpoint kinase 2
MGI:1355321
5 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Chek2tm1Mak/Chek2tm1Mak
involves: 129P2/OlaHsd 		decreased cellular sensitivity to ionizing radiation J:126186
Chek2tm1Mak/Chek2tm1Mak
involves: 129P2/OlaHsd * C57BL/6 		abnormal cell cycle checkpoint function J:78491
decreased cellular sensitivity to gamma-irradiation J:78491
increased incidence of tumors by chemical induction J:78491
Chek2tm1Nmt/Chek2tm1Nmt
involves: 129P2/OlaHsd * C57BL/6J 		decreased cellular sensitivity to ionizing radiation J:88888
decreased mortality induced by ionizing radiation J:88888
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory