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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Socs1
suppressor of cytokine signaling 1
MGI:1354910
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ifngtm1Ts/Ifng+
Socs1tm1Wehi/Socs1tm1Wehi
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 		decreased survivor rate J:57474
premature death J:57474
Ifngtm1Ts/Ifngtm1Ts
Socs1tm1Jni/Socs1tm1Jni
involves: 129S7/SvEvBrd 		increased interleukin-17 secretion J:132905
Ifngtm1Ts/Ifngtm1Ts
Socs1tm1Wehi/Socs1tm1Wehi
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 		abnormal lactation J:70408
abnormal lung vasculature morphology J:57474
abnormal mammary gland growth during pregnancy J:70408
enlarged thymus medulla J:57474
normal hematopoietic system phenotype J:57474
mammary gland alveolar hyperplasia J:70408
normal mortality/aging J:57474, J:70408
Prlrtm1Cnp/Prlr+
Socs1tm1Wehi/Socs1+
involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas * C57BL/6 		normal endocrine/exocrine gland phenotype J:70408
normal reproductive system phenotype J:70408
Socs1tm1Kish/Socs1tm1Kish
Stat1tm1Rds/Stat1tm1Rds
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		decreased body size J:69472
enlarged liver J:69472
normal immune system phenotype J:69472
increased activated T cell number J:69472
liver inflammation J:69472
postnatal growth retardation J:69472
premature death J:69472
thymus atrophy J:69472
Socs1tm1Kish/Socs1tm1Kish
Stat6tm1Aki/Stat6tm1Aki
involves: 129P2/OlaHsd * C57BL/6 		decreased body size J:69472
enlarged liver J:69472
normal immune system phenotype J:69472
increased activated T cell number J:69472
liver inflammation J:69472
postnatal growth retardation J:69472
premature death J:69472
thymus atrophy J:69472
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory