Tmprss2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmprss2
transmembrane protease, serine 2
MGI:1354381

15 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmprss2^{tm1(KOMP)Vlcg}/Tmprss2^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal cytokine secretion	J:283077
	decreased susceptibility to Coronaviridae infection	J:283077
	decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:214427
	normal embryo phenotype	J:214427
	normal growth/size/body region phenotype	J:214427
	lung inflammation	J:214427
	normal reproductive system phenotype	J:214427
Tmprss2^tm1Psn/Tmprss2^tm1Psn B6JRj.129S1-Tmprss2^tm1Psn	decreased susceptibility to Orthomyxoviridae infection	J:287633
Tmprss2^tm1Psn/Tmprss2^tm1Psn B6JRj.129S1-Tmprss2^tm1Psn	decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:287633
Tmprss2^tm1Psn/Tmprss2^tm1Psn involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:105558
Tmprss2^tm1Psn/Tmprss2^tm1Psn involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	decreased susceptibility to Orthomyxoviridae infection	J:244166
Tmprss2^{tm2b(EUCOMM)Hmgu}/Tmprss2^{tm2b(EUCOMM)Hmgu} C57BL/6N-Tmprss2^{tm2b(EUCOMM)Hmgu}/Orl	abnormal auditory brainstem response	J:211773
	abnormal contextual conditioning behavior	J:211773
	decreased cardiac muscle contractility	J:211773
	improved glucose tolerance	J:211773
	increased circulating total protein level	J:211773
	increased fasting circulating glucose level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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