Ebi3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ebi3
Epstein-Barr virus induced gene 3
MGI:1354171

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ebi3^Gt716Lex/Ebi3^Gt716Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal CD4-positive, alpha-beta T cell number	J:286951
	abnormal T cell activation	J:286951
	astrocytosis	J:286951
	brain inflammation	J:286951
	decreased interleukin-10 secretion	J:286951
	increased CD8-positive, alpha-beta T cell number	J:286951
	increased interferon-gamma secretion	J:286951
	increased macrophage cell number	J:286951
	increased susceptibility to Coronaviridae infection	J:286951
	increased susceptibility to Coronaviridae infection induced morbidity/mortality	J:286951
Ebi3^tm1Rsb/Ebi3^tm1Rsb involves: 129X1/SvJ * C57BL/6	abnormal immune system morphology	J:81014
	abnormal immune system physiology	J:81014
	abnormal T-helper 1 cell morphology	J:97822
	abnormal T-helper 2 cell morphology	J:97822
	decreased interleukin-4 secretion	J:81014
	decreased NK cell number	J:81014
	decreased susceptibility to induced colitis	J:81014
	decreased T-helper 2 cell number	J:81014
	increased interferon-gamma secretion	J:81014
	increased susceptibility to parasitic infection	J:97822

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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