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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
MGI:1353449
12 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Eif2ak2tm1Ajs/Eif2ak2tm1Ajs
involves: 129
abnormal cell physiology J:187314
Eif2ak2tm1Cwe/Eif2ak2tm1Cwe
involves: 129
normal immune system phenotype J:114555
Eif2ak2tm1Cwe/Eif2ak2tm1Cwe
involves: 129S/SvEv * C57BL/6
increased interleukin-4 secretion J:66112
increased susceptibility to type IV hypersensitivity reaction J:66112
increased susceptibility to viral infection J:30617
increased T cell proliferation J:66112
Eif2ak2tm1Jcbe/Eif2ak2tm1Jcbe
involves: 129S4/SvJae
decreased sensitivity to induced cell death J:63671
normal immune system phenotype J:63671
increased sensitivity to induced cell death J:63671
increased sensitivity to induced morbidity/mortality J:63671
increased susceptibility to viral infection J:63671, J:167126
Eif2ak2tm1Jcbe/Eif2ak2tm1Jcbe
involves: 129S4/SvJae * BALB/c
normal cellular phenotype J:53258
decreased erythroid progenitor cell number J:53258
normal immune system phenotype J:53258
normal neoplasm J:53258

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory