Nr4a1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr4a1
nuclear receptor subfamily 4, group A, member 1
MGI:1352454

25 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Nr4a1^tm1Pcn/Nr4a1^tm1Pcn Nr4a3^em1Juz/Nr4a3^em1Juz involves: 129 * BALB/c * C57BL/6	decreased B cell apoptosis	J:306652
	normal immune system phenotype	J:306652
	increased B cell proliferation	J:306652
Ifi27^tm1Npm/Ifi27^tm1Npm Nr4a1^tm1Jmi/Nr4a1^tm1Jmi involves: 129 * C57BL/6 * Swiss Webster	normal cardiovascular system phenotype	J:212520
Nr4a1^tm1Jmi/Nr4a1^tm1Jmi Nr4a3^tm1Omc/Nr4a3^tm1Omc involves: 129S/SvEv * 129S2/SvPas * C57BL/6	abnormal bone marrow cell number	J:121903
	abnormal common myeloid progenitor cell morphology	J:121903
	abnormal leukopoiesis	J:121903
	abnormal myelopoiesis	J:121903
	abnormal spleen morphology	J:121903
	abnormal thymus morphology	J:121903
	anemia	J:121903
	decreased body size	J:121903
	decreased lymphocyte cell number	J:121903
	enlarged liver	J:121903
	enlarged lymph nodes	J:121903
	enlarged spleen	J:121903
	hunched posture	J:121903
	increased eosinophil cell number	J:121903
	increased granulocyte number	J:121903
	increased hematopoietic stem cell number	J:121903
	increased leukemia incidence	J:121903
	increased leukocyte cell number	J:121903
	increased neutrophil cell number	J:121903
	postnatal lethality, complete penetrance	J:121903
	ruffled hair	J:121903

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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