Abcc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcc2
ATP-binding cassette, sub-family member 2
MGI:1352447

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abcc2^tm1Ahs/Abcc2^tm1Ahs B6.129P2(FVB)-Abcc2^tm1Ahs	increased circulating bilirubin level	J:208127
Abcc2^tm1Ahs/Abcc2^tm1Ahs B6.129P2(FVB)-Abcc2^tm1Ahs	increased physiological sensitivity to xenobiotic	J:208127
Abcc2^tm1Ahs/Abcc2^tm1Ahs FVB.129P2-Abcc2^tm1Ahs	abnormal xenobiotic pharmacokinetics	J:107822
	bilirubinuria	J:216646
	increased circulating bilirubin level	J:216646
Abcc2^tm1Ahs/Abcc2^tm1Ahs involves: 129P2/OlaHsd * FVB	abnormal bile secretion	J:107822
	abnormal blood homeostasis	J:107822
	abnormal kidney physiology	J:107822
	abnormal liver physiology	J:107822
	abnormal xenobiotic pharmacokinetics	J:107822
	bilirubinuria	J:107822
	decreased hemoglobin content	J:107822
	increased circulating bilirubin level	J:107822
	increased liver weight	J:107822
Abcc2^tm1Dgen/Abcc2^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal bile composition	J:134950
	abnormal bile secretion	J:134950
	abnormal liver physiology	J:134950
	decreased circulating alkaline phosphatase level	J:134950
	increased circulating bilirubin level	J:134950
	increased circulating cholesterol level	J:134950
Abcc2^{tm2b(KOMP)Wtsi}/Abcc2^{tm2b(KOMP)Wtsi} C57BL/6N-Abcc2^{tm2b(KOMP)Wtsi}/H	decreased lymphocyte cell number	J:211773
	decreased mean corpuscular volume	J:211773
	decreased mean platelet volume	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating bilirubin level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased kidney weight	J:211773
	increased neutrophil cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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