Racgap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Racgap1
Rac GTPase-activating protein 1
MGI:1349423

25 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Racgap1^{Gt(pSABetageo)11Huy}/Racgap1^{Gt(pSABetageo)11Huy} involves: 129X1/SvJ * C57BL/6	abnormal blastocyst morphology	J:69359
	absent inner cell mass	J:69359
	embryonic lethality before implantation, complete penetrance	J:69359
	failure of zygotic cell division	J:69359
Racgap1^tm1Mahi/Racgap1^tm1Mahi Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal B cell differentiation	J:137760
	abnormal definitive hematopoiesis	J:137760
	abnormal erythrocyte morphology	J:137760
	abnormal myelopoiesis	J:137760
	decreased bone marrow cell number	J:137760
	decreased pro-B cell number	J:137760
	decreased transitional stage B cell number	J:137760
	premature death	J:137760
Racgap1^tm1Mahi/Racgap1^tm1Mahi Tg(Stra8-icre)1Reb/0 involves: C57BL/6 * FVB/NJ	abnormal seminiferous tubule morphology	J:206583
	abnormal Sertoli cell morphology	J:206583
	abnormal spermatogonia morphology	J:206583
	abnormal spermatogonia proliferation	J:206583
	abnormal testis physiology	J:206583
	arrest of spermatogenesis	J:206583
	azoospermia	J:206583
	decreased male germ cell number	J:206583
	decreased testis weight	J:206583
	male infertility	J:206583
	multinucleated giant male germ cells	J:206583
	seminiferous tubule degeneration	J:206583
	small testis	J:206583

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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