Sdc4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sdc4
syndecan 4
MGI:1349164

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sdc4^tm1Goe/Sdc4⁺ involves: 129S4/SvJae * C57BL/6	decreased angiogenesis	J:67007
	decreased fibroblast cell migration	J:67007
	delayed wound healing	J:67007
	impaired wound healing	J:67007
Sdc4^tm1Goe/Sdc4^tm1Goe involves: 129S4/SvJae * C57BL/6	decreased angiogenesis	J:67007
	decreased fibroblast cell migration	J:67007
	delayed wound healing	J:67007
	impaired wound healing	J:67007
Sdc4^tm1Tmu/Sdc4^tm1Tmu B6.129S2-Sdc4^tm1Tmu	abnormal kidney inner medulla morphology	J:68843
	abnormal placental labyrinth vasculature morphology	J:65874
	dilated renal tubule	J:68843
	increased blood urea nitrogen level	J:68843
	increased physiological sensitivity to xenobiotic	J:68843, J:131075
	increased susceptibility to xenobiotic induced morbidity/mortality	J:68843, J:131075
	kidney degeneration	J:68843
Sdc4^tm1Tmu/Sdc4^tm1Tmu involves: 129S2/SvPas	normal cardiovascular system phenotype	J:276769
Sdc4^tm1Tmu/Sdc4^tm1Tmu involves: 129S2/SvPas * C57BL/6J	abnormal cell adhesion	J:60596
Sdc4^{tm2b(KOMP)Wtsi}/Sdc4⁺ C57BL/6N-Sdc4^{tm2b(KOMP)Wtsi}/H	abnormal retina blood vessel morphology	J:211773
	mydriasis	J:211773
Sdc4^{tm2b(KOMP)Wtsi}/Sdc4^{tm2b(KOMP)Wtsi} C57BL/6N-Sdc4^{tm2b(KOMP)Wtsi}/H	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased lymphocyte cell number	J:211773
	decreased mean platelet volume	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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