Ror2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ror2
receptor tyrosine kinase-like orphan receptor 2
MGI:1347521

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bax^tm1Sjk/Bax^tm1Sjk Ror2^Y324C/Ror2^Y324C involves: 129X1/SvJ * C57BL/6J	abnormal primordial germ cell migration	J:179805
	abnormal primordial germ cell morphology	J:179805
	decreased primordial germ cell number	J:179805
Pgr^tm2(cre)Lyd/Pgr⁺ Ror1^tm1.1Meg/Ror1^tm1.1Meg Ror2^tm1.1Meg/Ror2^tm1.1Meg involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	abnormal embryo attachment	J:233595
	abnormal maternal decidual layer morphology	J:233595
	decreased litter size	J:233595
	reduced female fertility	J:233595
Ror1^tm1.1Meg/Ror1^tm1.1Meg Ror2^tm1.1Meg/Ror2^tm1.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJae * C57BL/6J * CBA/J	abnormal sympathetic neuron innervation pattern	J:182150
Ror1^tm1.2Meg/Ror1^tm1.2Meg Ror2^tm1.2Meg/Ror2^tm1.2Meg involves: 129S4/SvJae * C57BL/6 * FVB/N	abnormal facial morphology	J:182150
	caudal body truncation	J:182150
	exencephaly	J:182150
	hydrops fetalis	J:182150
	lethality throughout fetal growth and development, complete penetrance	J:182150
	short limbs	J:182150
Ror1^tm1Ymi/Ror1^tm1Ymi Ror2^tm1Ymi/Ror2^tm1Ymi involves: 129P2/OlaHsd * C57BL/6	abnormal cartilage development	J:72948
	abnormal cartilage morphology	J:72948
	abnormal chondrocyte morphology	J:72948
	abnormal long bone morphology	J:72948
	abnormal pubic symphysis morphology	J:72948
	absent sternum	J:72948
	perinatal lethality, incomplete penetrance	J:72948
	transposition of great arteries	J:72948
	ventricular septal defect	J:72948

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23