Parg Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Parg
poly (ADP-ribose) glycohydrolase
MGI:1347094

16 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Parg^tm1Tmd/Parg^tm1Tmd involves: 129X1/SvJ	decreased cell proliferation	J:95214
	embryonic lethality between implantation and somite formation, complete penetrance	J:95214
	failure of blastocyst to hatch from the zona pellucida	J:95214
	increased apoptosis	J:95214
Parg^tm1Zqw/Parg^tm1Zqw involves: 129P2/OlaHsd * C57BL/6	abnormal pancreatic beta cell morphology	J:92244
	increased circulating glucose level	J:92244
	increased circulating tumor necrosis factor level	J:92244
	increased mortality induced by gamma-irradiation	J:92244
	increased susceptibility to endotoxin shock	J:92244
	increased susceptibility to xenobiotic induced morbidity/mortality	J:92244
Parg^{tm2b(KOMP)Mbp}/Parg⁺ C57BL/6N-Parg^{tm2b(KOMP)Mbp}/J	decreased leukocyte cell number	J:211773
Parg^{tm2b(KOMP)Mbp}/Parg⁺ C57BL/6N-Parg^{tm2b(KOMP)Mbp}/Tcp	hydrometra	J:211773
	small superior vagus ganglion	J:211773
Parg^{tm2b(KOMP)Mbp}/Parg^{tm2b(KOMP)Mbp} C57BL/6N-Parg^{tm2b(KOMP)Mbp}/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Parg^{tm2b(KOMP)Mbp}/Parg^{tm2b(KOMP)Mbp} C57BL/6N-Parg^{tm2b(KOMP)Mbp}/Tcp	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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