Txnrd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Txnrd2
thioredoxin reductase 2
MGI:1347023

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myl2^tm1(cre)Krc/Myl2⁺ Txnrd2^tm1Marc/Txnrd2^tm1.1Marc involves: 129P2/OlaHsd * C57BL/6	abnormal myocardial fiber morphology	J:94136
	congestive heart failure	J:94136
	dilated heart atrium	J:94136
	edema	J:94136
	globular heart	J:94136
	liver vascular congestion	J:94136
	neonatal lethality, complete penetrance	J:94136
	thin ventricular wall	J:94136
Txnrd2^tm1.1Marc/Txnrd2^tm1.1Marc involves: 129P2/OlaHsd * C57BL/6	abnormal blood flow velocity	J:94136
	abnormal definitive hematopoiesis	J:94136
	abnormal heart morphology	J:94136
	abnormal liver morphology	J:94136
	anemia	J:94136
	decreased fetal cardiomyocyte proliferation	J:94136
	decreased fibroblast proliferation	J:94136
	embryonic lethality during organogenesis, complete penetrance	J:94136
	thin interventricular septum	J:94136
	thin ventricular wall	J:94136
	trabecula carnea hypoplasia	J:94136
Txnrd2^tm1Marc/Txnrd2^tm1Marc Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	normal nervous system phenotype	J:133173
	no abnormal phenotype detected	J:133173

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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