Mta2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mta2
metastasis-associated gene family, member 2
MGI:1346340

30 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mta2^tm1.1Yzha/Mta2^tm1.1Yzha involves: 129S4/SvJae * C57BL/6 * FVB/N	abnormal axial skeleton morphology	J:137101
	abnormal craniofacial morphology	J:137101
	acanthosis	J:137101
	decreased body size	J:137101
	decreased hair follicle number	J:137101
	decreased survivor rate	J:137101
	dermatitis	J:137101
	embryonic lethality, incomplete penetrance	J:137101
	female infertility	J:137101
	glomerulonephritis	J:137101
	normal homeostasis/metabolism phenotype	J:137101
	hyperkeratosis	J:137101
	increased anti-double stranded DNA antibody level	J:137101
	increased autoantibody level	J:137101
	increased circulating alanine transaminase level	J:137101
	increased circulating interferon-gamma level	J:137101
	increased circulating interleukin-2 level	J:137101
	increased circulating interleukin-4 level	J:137101
	increased kidney cell proliferation	J:137101
	increased mesangial cell number	J:137101
	increased susceptibility to systemic lupus erythematosus	J:137101
	increased T cell proliferation	J:137101
	increased urine protein level	J:137101
	liver inflammation	J:137101
	panniculitis	J:137101
	perinatal lethality, incomplete penetrance	J:137101
	premature death	J:137101
	skin inflammation	J:137101
	skin lesions	J:137101
Mta2^{tm1a(EUCOMM)Wtsi}/Mta2^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	embryonic lethality, incomplete penetrance	J:278486
Mta2^tm1Yzha/Mta2^tm1Yzha Tg(Lck-cre)#Zhu/0 involves: 129S4/SvJae * C57BL/6 * SJL	normal immune system phenotype	J:137101
	increased T cell proliferation	J:137101

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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