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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gdf15
growth differentiation factor 15
MGI:1346047
32 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gdf15tm1Breit/Gdf15tm1Breit
B6.Cg-Gdf15tm1Breit
abnormal basal metabolism J:197174
decreased energy expenditure J:197174
decreased lean body mass J:197174
decreased locomotor activity J:197174
normal homeostasis/metabolism phenotype J:197174
increased body weight J:197174
increased food intake J:197174
increased inguinal fat pad weight J:197174
increased mesenteric fat pad weight J:197174
increased retroperitoneal fat pad weight J:197174
increased total body fat amount J:197174
increased white adipose tissue amount J:197174
Gdf15tm1Kuns/Gdf15tm1Kuns
involves: 129S2/SvPas * C57BL/6
abnormal facial nerve morphology J:154446
abnormal L4 dorsal root ganglion morphology J:154446
abnormal L5 dorsal root ganglion morphology J:154446
abnormal somatic nervous system morphology J:154446
abnormal trigeminal nerve morphology J:154446
decreased motor neuron number J:154446
decreased neuron number J:154446
decreased sensory neuron number J:154446
impaired coordination J:154446
increased body weight J:154446
Gdf15tm1Sjl/Gdf15tm1Sjl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal kidney morphology J:202996
decreased bleeding time J:195443
decreased body weight J:202996
normal homeostasis/metabolism phenotype J:61788
increased fluid intake J:202996
increased food intake J:202996
increased kidney weight J:202996
increased myocardial infarct size J:118878
increased platelet aggregation J:195443
increased susceptibility to induced morbidity/mortality J:195443
increased susceptibility to induced thrombosis J:195443
increased urine glucose level J:202996
polyuria J:202996

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory