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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Akt3
thymoma viral proto-oncogene 3
MGI:1345147
18 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Akt3Nmf350/Akt3+
C57BL/6J-Akt3Nmf350
abnormal seizure response to electrical stimulation J:169028
increased brain size J:169028
increased brain weight J:169028
increased susceptibility to pharmacologically induced seizures J:169028
maximal tonic hindlimb extension seizures J:169028
sporadic seizures J:169028
tonic-clonic seizures J:169028
Akt3Nmf350/Akt3Nmf350
C57BL/6J-Akt3Nmf350
abnormal neuron morphology J:169028
abnormal seizure response to electrical stimulation J:169028
absent corpus callosum J:169028
ectopic cerebellar granule cells J:169028
enlarged hippocampus J:169028
increased brain size J:169028
increased brain weight J:169028
increased susceptibility to pharmacologically induced seizures J:169028
maximal tonic hindlimb extension seizures J:169028
tonic-clonic seizures J:169028
Akt3tm1Hem/Akt3tm1Hem
involves: 129P2/OlaHsd * C57BL/6
abnormal brain ventricle morphology J:98804
decreased brain size J:98804
decreased brain weight J:98804
decreased corpus callosum size J:98804
increased susceptibility to neuronal excitotoxicity J:98804
Akt3tm1Mbb/Akt3tm1Mbb
involves: C57BL/6J
abnormal seizure response to electrical stimulation J:169028
maximal tonic hindlimb extension seizures J:169028
tonic-clonic seizures J:169028
Akt3tm1Mbb/Akt3tm1Mbb
Not Specified
decreased brain size J:96823
normal homeostasis/metabolism phenotype J:96823
normal immune system phenotype J:135903

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory