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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ldb3
LIM domain binding 3
MGI:1344412
49 phenotypes from 7 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ldb3tm1Chen/Ldb3tm1Chen
involves: 129S1/Sv * 129X1/SvJ * Black Swiss 		abnormal myocardium layer morphology J:72799
abnormal skeletal muscle morphology J:72799
cyanosis J:72799
dilated heart left ventricle J:72799
dilated heart right ventricle J:72799
dysphagia J:72799
heart vascular congestion J:72799
impaired limb coordination J:72799
muscle weakness J:72799
myopathy J:72799
neonatal lethality, incomplete penetrance J:72799
postnatal lethality, complete penetrance J:72799
respiratory distress J:72799
Ldb3tm2b(EUCOMM)Hmgu/Ldb3+
C57BL/6N-Ldb3tm2b(EUCOMM)Hmgu/Bay 		decreased locomotor activity J:211773
enlarged kidney J:211773
increased basophil cell number J:211773
increased large unstained cell number J:211773
prolonged QRS complex duration J:211773
small seminal vesicle J:211773
Ldb3tm2b(EUCOMM)Hmgu/Ldb3tm2b(EUCOMM)Hmgu
C57BL/6N-Ldb3tm2b(EUCOMM)Hmgu/Bay 		preweaning lethality, complete penetrance J:211773
Ldb3tm2Chen/Ldb3tm2Chen
involves: 129S1/Sv * 129X1/SvJ * Black Swiss 		abnormal skeletal muscle morphology J:82141
cardiac fibrosis J:82141
decreased body weight J:82141
increased variability of skeletal muscle fiber size J:82141
myopathy J:82141
postnatal lethality, incomplete penetrance J:82141
skeletal muscle fiber atrophy J:82141
Ldb3tm3Chen/Ldb3tm3Chen
involves: 129S1/Sv * 129X1/SvJ * Black Swiss 		abnormal skeletal muscle morphology J:82141
cardiac fibrosis J:82141
decreased body weight J:82141
increased variability of skeletal muscle fiber size J:82141
myopathy J:82141
postnatal lethality, incomplete penetrance J:82141
skeletal muscle fiber atrophy J:82141
Ldb3tm4Chen/Ldb3tm4Chen
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * FVB/N 		abnormal cardiovascular system physiology J:144739
dilated cardiomyopathy J:144739
dilated heart left ventricle J:144739
dilated heart right ventricle J:144739
enlarged heart J:144739
premature death J:144739
Ldb3tm4Chen/Ldb3tm4Chen
Myl2tm1(cre)Krc/Myl2+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss 		abnormal heart left ventricle morphology J:144739
abnormal heart right ventricle morphology J:144739
abnormal heart ventricle morphology J:144739
abnormal myocardial fiber morphology J:144739
atrioventricular block J:144739
cardiac hypertrophy J:144739
dilated cardiomyopathy J:144739
enlarged heart J:144739
increased heart weight J:144739
premature death J:144739
thin interventricular septum J:144739
thin ventricular wall J:144739
Ldb3tm5.2Chen/Ldb3tm5.2Chen
involves: 129/Sv * Black Swiss * C57BL/6 * SJL 		normal cardiovascular system phenotype J:170494
Ldb3tm6.2Chen/Ldb3tm6.2Chen
involves: 129/Sv * Black Swiss * C57BL/6 * SJL 		abnormal heart morphology J:170494
abnormal Z line morphology J:170494
cardiac fibrosis J:170494
decreased body size J:170494
decreased cardiac muscle contractility J:170494
decreased heart left ventricle posterior wall thickness J:170494
dilated cardiomyopathy J:170494
increased heart left ventricle size J:170494
increased heart left ventricle weight J:170494
increased heart right ventricle size J:170494
increased heart weight J:170494
increased response of heart to induced stress J:170494
postnatal growth retardation J:170494
postnatal lethality, incomplete penetrance J:170494
premature death J:170494
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory