Msh6 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Msh6
mutS homolog 6
MGI:1343961

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Msh3^tm1Htr/Msh3^tm1Htr Msh6^tm1Htr/Msh6^tm1Htr involves: 129P2/OlaHsd * FVB/N	decreased tumor-free survival time	J:59561
	increased gastrointestinal tumor incidence	J:59561
	increased lymphoma incidence	J:59561
	increased skin tumor incidence	J:59561
Msh3^tm1Rak/Msh3^tm1Rak Msh6^tm1Rak/Msh6^tm1Rak involves: 129/Sv * C57BL/6J * SJL	abnormal mismatch repair	J:60604
	increased gastrointestinal tumor incidence	J:60604
	increased intestinal adenocarcinoma incidence	J:60604
	increased lymphoma incidence	J:60604
	premature death	J:60604

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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