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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Msh6
mutS homolog 6
MGI:1343961
11 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Msh6m1Btlr/Msh6m1Btlr
C57BL/6J-Msh6m1Btlr
decreased IgE level J:255208
Msh6tm1Htr/Msh6tm1Htr
involves: 129P2/OlaHsd * FVB/N
decreased tumor-free survival time J:59561
increased gastrointestinal tumor incidence J:59561
increased hemolymphoid system tumor incidence J:59561
increased lymphoma incidence J:59561
increased skin tumor incidence J:59561
increased uterus tumor incidence J:59561
Msh6tm1Rak/Msh6tm1Rak
involves: 129/Sv * C57BL/6J * SJL
increased gastrointestinal tumor incidence J:44428
increased lymphoma incidence J:44428
increased tumor incidence J:44428
premature death J:44428
Msh6tm1Wed/Msh6+
involves: 129/Sv * C57BL/6J * SJL
increased lymphoma incidence J:92555
Msh6tm1Wed/Msh6tm1Wed
involves: 129/Sv * C57BL/6J * SJL
decreased tumor-free survival time J:92555
increased basal cell carcinoma incidence J:92555
increased intestinal adenoma incidence J:92555
increased lymphoma incidence J:92555
increased tumor incidence J:92555

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory