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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hpse
heparanase
MGI:1343124
12 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hpsetm1.2Mdh/Hpsetm1.2Mdh
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal dendritic cell chemotaxis J:209913
abnormal Langerhans cell morphology J:209913
abnormal lung epithelium morphology J:209913
decreased acute inflammation J:209913
decreased leukocyte cell number J:209913
impaired eosinophil recruitment J:209913
increased eosinophil cell number J:209913
Hpsetm1b(EUCOMM)Hmgu/Hpsetm1b(EUCOMM)Hmgu
C57BL/6N-Hpsetm1b(EUCOMM)Hmgu/Tcp 		increased circulating creatinine level J:211773
Hpsetm1Jpli/Hpsetm1Jpli
B6.129-Hpsetm1Jpli 		abnormal mammary gland development J:148281
increased angiogenesis J:148281
increased hemoglobin content J:148281
pathological neovascularization J:148281
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory